The Effect of Vitamin C on Tooth Growth in Guinea Pigs

The response is the length of odontoblasts (cells responsible for tooth growth) in 60 guinea pigs. Each animal received one of three dose levels of vitamin C (0.5, 1, and 2 mg/day) by one of two delivery methods, (orange juice or ascorbic acid (a form of vitamin C and coded as VC).

Usage

ToothGrowth

Format

A data frame with 60 observations on 3 variables.

R project statistics dataset table

[,1]	len	numeric	Tooth length
[,2]	supp	factor	Supplement type (VC or OJ).
[,3]	dose	numeric	Dose in milligrams/day

Source

C. I. Bliss (1952) The Statistics of Bioassay. Academic Press.

References

McNeil, D. R. (1977) Interactive Data Analysis. New York: Wiley.

Crampton, E. W. (1947) The growth of the odontoblast of the incisor teeth as a criterion of vitamin C intake of the guinea pig. The Journal of Nutrition 33(5): 491–504. http://jn.nutrition.org/content/33/5/491.full.pdf

Examples

require(graphics)
coplot(len ~ dose | supp, data = ToothGrowth, panel = panel.smooth,
       xlab = "ToothGrowth data: length vs dose, given type of supplement")